September 2011. Volume 7. Number 3

Some tests for the detection of Helicobacter pylori antigens in stools are accurate enough in children

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Leal YA, Cedillo-Rivera R, Simón JA, Velázquez JR, Flores LL, Torres J. Utility of stool sample-based test for the diagnosis of helicbacter pylori infection in children. J Pediatr Gastroenterol Nutr. 2011;52:718-28.
Reviewers: Andrés de Llano JM1, Ochoa Sangrador C2.
1Servicio de Pediatría. Hospital General del Río Carrión. Palencia. España.
2Servicio de Pediatría. Hospital Virgen de la Concha. Zamora. España.
Correspondence: Jesús María Andrés de Llano. Email: jmandres@ono.com
Reception date: 22/07/2011
Acceptance date: 25/07/2011
Publication date: 27/07/2011

Abstract

Authors' conclusions: the detection of Helicobacter pylori antigen in stools with ELISA monoclonal antibodies is a noninvasive accurate test for the diagnosis of infection in children. One-step tests showed low accuracy and more studies are needed to obtain a useful office-based screening test. The available molecular tests are still unreliable.

Reviewers' commentary: the screening of antigens of Helicobacter pylori in stools, especially those based on ELISA with monoclonal antibodies, are accurate enough, but enough information about its usefulness in young children is lacking. These tests will be useful as an adjunct in the diagnosis and control of the eradication of the infection; although currently they cannot replace the endoscopy in the diagnosis and treatment of peptic disease by H. pylori.

How to cite this article

Ochoa Sangrador C, Andrés de Llano JM. Algunas pruebas de detección de antígeno de Helicobacter pylori en heces son suficientemente válidas en la infancia. Evid Pediatr. 2011;7:65.

AVC | Critically appraised articles

Leal YA, Cedillo-Rivera R, Simón JA, Velázquez JR, Flores LL, Torres J. Utility of stool sample-based test for the diagnosis of helicbacter pylori infection in children. J Pediatr Gastroenterol Nutr. 2011;52:718-28.
Reviewers: Andrés de Llano JM1, Ochoa Sangrador C2.
1Servicio de Pediatría. Hospital General del Río Carrión. Palencia. España.
2Servicio de Pediatría. Hospital Virgen de la Concha. Zamora. España.
Correspondence: Jesús María Andrés de Llano. Email: jmandres@ono.com
Reception date: 22/07/2011
Acceptance date: 25/07/2011
Publication date: 27/07/2011

How to cite this article

Ochoa Sangrador C, Andrés de Llano JM. Algunas pruebas de detección de antígeno de Helicobacter pylori en heces son suficientemente válidas en la infancia. Evid Pediatr. 2011;7:65.

References

  1. Spee LAA, Madderom MB, Pijpers M, van Leeuwen Y, Berger MY. Association between Helicobacter pylori and gastrointestinal symptoms in children. Pediatrics. 2010;125:e651-69.
  2. Carreazo Pariasca NY, Cuervo Valdés JJ. El Helicobacter pylori no parece jugar un papel importante en la patología gastrointestinal en la infancia. Evid Pediatr. 2010;6:31.
  3. Molina Arias M, Martinez-Ojinaga E. Helicobacter pylori. Tras la tempestad, ¿vendrá la calma? Evid Pediatr. 2010;6:26.
27/07/2011

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