March 2014. Volume 10. Number 1

What clinical impact has the use of probiotics on infantile colics?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Anabrees J, Indrio F, Paes B, Alfaleh K. Probiotics for infantile colic: a systematic review. BMC Pediatr. 2013;13:186.
Reviewers: Jullien S1, Llerena Santa Cruz E2.
1Servicio de Pediatría. Hospital Universitario de Girona Dr. Josep Trueta. Girona. España.
2Servicio de Pediatría. Hospital Universitario Dr. Josep Trueta. Girona. Girona. España.
Correspondence: Sophie Jullien. Email: sophjullien@gmail.com
Reception date: 28/12/2013
Acceptance date: 03/01/2014
Publication date: 19/02/2014

Abstract

Authors’ conclusions: although L. reuteri may be effective as a treatment strategy for crying in exclusively breastfed infants with colic, the evidence supporting probiotic use for the treatment of infant colic or crying in formula-fed infants remains unresolved. Results from larger rigorously designed studies will help draw more definitive conclusions.

Reviewers’ commentary: L reuteri is useful in reducing the time of infant crying. It reduces an average of 55 minutes per day, but only in mothers with exclusive breastfeeding and milk protein-free diet. It is still premature to generalize these results, and it is not known if this strain will work in different populations, or if it is cost-effective to give this treatment for 21 days.

How to cite this article

Jullien S, Llerena Santa Cruz E. ¿Qué impacto clínico tiene la utilización de probióticos en los cólicos del lactante? Evid Pediatr. 2014;10:13.

AVC | Critically appraised articles

Anabrees J, Indrio F, Paes B, Alfaleh K. Probiotics for infantile colic: a systematic review. BMC Pediatr. 2013;13:186.
Reviewers: Jullien S1, Llerena Santa Cruz E2.
1Servicio de Pediatría. Hospital Universitario de Girona Dr. Josep Trueta. Girona. España.
2Servicio de Pediatría. Hospital Universitario Dr. Josep Trueta. Girona. Girona. España.
Correspondence: Sophie Jullien. Email: sophjullien@gmail.com
Reception date: 28/12/2013
Acceptance date: 03/01/2014
Publication date: 19/02/2014

How to cite this article

Jullien S, Llerena Santa Cruz E. ¿Qué impacto clínico tiene la utilización de probióticos en los cólicos del lactante? Evid Pediatr. 2014;10:13.

References

  1. Savino F, Pelle E, Palumeri E, Oggero R, Miniero R. Lactobacillus reuteri versus simethicone in the treatment of infantile colic: a prospective randomized study. Pediatrics. 2007;119:e124-30.
  2. Savino F, Cordisco L, Tarasco V, Palumeri E, Calabrese R, Oggero R, et al. Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trial. Pediatrics. 2010;126:e526-33.
  3. Szajewska H, Gyrczuk E, Horvath A. Lactobacillus reuteri DSM 17938 for the management of infantile colic in breastfed infants: a randomized, double-blind, placebo-controlled trial. J Pediatr. 2013;162:257-62.
  4. Sung V, Collett S, de Gooyer T, Hiscock H, Tang M, Wake M. Probiotics to prevent or treat excessive infant crying: systematic review and meta-analysis. JAMA Pediatr. 2013;167:1150-7.
  5. Indrio F, Di Mauro A, Riezzo G, Civardi E, Intini C, Corvaglia L, et al. Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: A randomized clinical trial. JAMA Pediatr. 2014 [en prensa].
19/02/2014

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