September 2014. Volume 10. Number 3

The 13-Valent Pneumococcal Conjugate Vaccine is effective in reducing nasopharyngeal colonization by vaccine serotypes

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Gounder P, Bruce MC, Bruden DJT, Singleton RJ, Rudolph K, Hurlburt DA, et al. Effect of the 13-Valent Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization by Streptococcus pneumoniae-Alaska, 2008-2012. J Infect Dis. 2014;209:1251-8.
Reviewers: Martínez Rubio M.V1, Juanes de Toledo B2.
1CS Los Fresnos. Torrejón de Ardoz. Madrid. España.
2EAP Collado Villalba. Collado Villalba. Madrid. España.
Correspondence: M.ª Victoria Martínez Rubio. Email: victmrubio@gmail.com
Reception date: 29/04/2014
Acceptance date: 25/08/2014
Publication date: 03/09/2014

Abstract

Authors' conclusions: the 13-Valent Pneumococcal Conjugate Vaccine reduced colonization by the six new additional vaccine serotypes among children. Unvaccinated adults also experienced comparable reductions indicating substantial indirect protection from vaccine.

Reviewers' commentary: the 13-Valent Pneumococcal Conjugate Vaccine appears effective in reducing nasopharyngeal colonization by vaccine serotypes, although long-term studies should be done to confirm these results and their effect in decreasing rates of invasive pneumococcal disease.

How to cite this article

Martínez Rubio V, Juanes de Toledo B. La vacuna neumocócica 13-valente es eficaz reduciendo la colonización nasofaríngea por serotipos vacunales. Evid Pediatr. 2014;10:46.

AVC | Critically appraised articles

Gounder P, Bruce MC, Bruden DJT, Singleton RJ, Rudolph K, Hurlburt DA, et al. Effect of the 13-Valent Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization by Streptococcus pneumoniae-Alaska, 2008-2012. J Infect Dis. 2014;209:1251-8.
Reviewers: Martínez Rubio M.V1, Juanes de Toledo B2.
1CS Los Fresnos. Torrejón de Ardoz. Madrid. España.
2EAP Collado Villalba. Collado Villalba. Madrid. España.
Correspondence: M.ª Victoria Martínez Rubio. Email: victmrubio@gmail.com
Reception date: 29/04/2014
Acceptance date: 25/08/2014
Publication date: 03/09/2014

How to cite this article

Martínez Rubio V, Juanes de Toledo B. La vacuna neumocócica 13-valente es eficaz reduciendo la colonización nasofaríngea por serotipos vacunales. Evid Pediatr. 2014;10:46.

References

  1. Ruiz-Canela Caceres J, Juanes de Toledo B. Enfermedad neumocócica invasiva: aumento de la incidencia de serotipos no vacunales tras la vacunación universal de los niños nativos de Alaska. Evid Pediatr. 2007;3:74.
  2. Río-García MD, Molina Arias M. Resultados preliminares de la vacuna frente a 13 serotipos de neumococo. Evid Pediatr. 2013;9:28.
  3. Steens A, Bergsaker MA, Aaberge IS, Rønning K, Vestrheim DF. Prompteffect of replacing the 7-valent pneumococcal conjugate vaccine with the 13-valent vaccine on the epidemiology of invasive pneumococcal disease in Norway. Vaccine. 2013;31:6232-8.
03/09/2014

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