March 2015. Volume 11. Number 1

What markers are useful as predictors of renal scarring in children with urinary tract infection?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Shaikh N, Craig JC, Rovers MM, Da Dalt L, Gardikis S, Hoberman A, et al. Identification of children and adolescents at risk for renal scarring after a first urinary tract infection: a meta-analysis with individual patient data. JAMA Pediatr. 2014 Oct;168(10):893-900.
Reviewers: Pérez-Moneo Agapito B1, Ruiz-Canela Cáceres J2.
1Hospital Universitario Infanta Leonor. Madrid. España.
2CS Virgen de África. Sevilla. España.
Correspondence: Begoña Pérez-Moneo Agapito. Email: begopma@gmail.com
Reception date: 16/02/2015
Acceptance date: 02/03/2015
Publication date: 11/03/2015

Abstract

Authors’ conclusions: children with abnormal ultrasonographic results or a combination of high fever and an organism other than E. coli have a higher risk for the development of renal scarring after a first urinary tract infection.

Reviewers’ commentary: with the survey data only three clinical variables are a reasonable screening procedure for renal scarring: ultrasound, presence of fever> 39° and a different seed to E. coli in the culture properly obtained. Although due to the limitations of the study it should be tested in a prospective design. Systematic VCUG, according to this study and the recommendations of the GPC should only be performed on a small subset of patients, when indicated.

How to cite this article

Pérez-Moneo Agapito B, Ruiz-Canela Cáceres J. ¿Qué marcadores son útiles como predictores de cicatrices renales en niños con infección urinaria? Evid Pediatr. 2015;11:13.

AVC | Critically appraised articles

Shaikh N, Craig JC, Rovers MM, Da Dalt L, Gardikis S, Hoberman A, et al. Identification of children and adolescents at risk for renal scarring after a first urinary tract infection: a meta-analysis with individual patient data. JAMA Pediatr. 2014 Oct;168(10):893-900.
Reviewers: Pérez-Moneo Agapito B1, Ruiz-Canela Cáceres J2.
1Hospital Universitario Infanta Leonor. Madrid. España.
2CS Virgen de África. Sevilla. España.
Correspondence: Begoña Pérez-Moneo Agapito. Email: begopma@gmail.com
Reception date: 16/02/2015
Acceptance date: 02/03/2015
Publication date: 11/03/2015

How to cite this article

Pérez-Moneo Agapito B, Ruiz-Canela Cáceres J. ¿Qué marcadores son útiles como predictores de cicatrices renales en niños con infección urinaria? Evid Pediatr. 2015;11:13.

References

  1. Shaikh N, Ewing AL, Bhatnagar S, Hoberman A. Risk of renal scarring in children with a first urinary tract infection: a systematic review. Pediatrics. 2010;126:1084-91.
  2. Urinary tract infection in children. NICE guidelines. En: National Institute for Health and Care Excellence [en línea] [consultado el 02/03/2015]. Disponible en: http://www.nice.org.uk/CG54
  3. Subcommittee on Urinary Tract Infection, Steering Committee on Quality. Improvement and Management, Roberts KB. Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 months. Pediatrics. 2011;128:595-610.
  4. Grupo de trabajo de la Guía de Práctica Clínica sobre Infección del Tracto Urinario en la Población Pediátrica. Guía de Práctica Clínica sobre Infección del Tracto Urinario en la Población Pediátrica. Plan de Calidad para el Sistema Nacional de Salud del Ministerio de Sanidad, Política Social e Igualdad. Instituto Aragonés de Ciencias de la Salud; 2011. Guías de Práctica Clínica en el SNS: I+CS No 2009/01. Disponible en: http://www.guiasalud.es/GPC/GPC_483_ITU_poblacion_pediatrica_ICS_compl.pdf
11/03/2015

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