June 2015. Volume 11. Number 2

Cinnarizine may reduce migraine episodes in children

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Ashrafi MR, Salehi S, Malamiri RA, Heidari M, Hosseini SA, Samiei M, et al. Efficacy and safety of cinnarizine in the prophylaxis of migraine in children: a double-blind placebo-controlled randomized trial. Pediatr Neurol.2014;51:503-8.
Reviewers: Pérez Gaxiola G1, Rodríguez-Salinas Pérez E2.
1Hospital Pediátrico de Sinaloa. Culiacán. Sinaloa. México.
2CS Colmenar Viejo. Colmenar Viejo. Madrid. España.
Correspondence: Giordano Pérez Gaxiola. Email: giordanopg@gmail.com
Reception date: 24/03/2015
Acceptance date: 26/03/2015
Publication date: 08/04/2015

Abstract

Authors´ conclusions: cinnarizine is effective and safe for prophylaxis of migraine in children.

Reviewers´ commentary: although results suggest that cinnarizine is effective, uncertainty remains about their clinical relevance and precision.

How to cite this article

Pérez Gaxiola G, Rodríguez-Salinas Pérez E. La cinarizina parece disminuir las crisis de migraña en niños. Evid Pediatr. 2015;11:26.

AVC | Critically appraised articles

Ashrafi MR, Salehi S, Malamiri RA, Heidari M, Hosseini SA, Samiei M, et al. Efficacy and safety of cinnarizine in the prophylaxis of migraine in children: a double-blind placebo-controlled randomized trial. Pediatr Neurol.2014;51:503-8.
Reviewers: Pérez Gaxiola G1, Rodríguez-Salinas Pérez E2.
1Hospital Pediátrico de Sinaloa. Culiacán. Sinaloa. México.
2CS Colmenar Viejo. Colmenar Viejo. Madrid. España.
Correspondence: Giordano Pérez Gaxiola. Email: giordanopg@gmail.com
Reception date: 24/03/2015
Acceptance date: 26/03/2015
Publication date: 08/04/2015

How to cite this article

Pérez Gaxiola G, Rodríguez-Salinas Pérez E. La cinarizina parece disminuir las crisis de migraña en niños. Evid Pediatr. 2015;11:26.

References

  1. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders: 2nd edition. Cephalalgia. 2004;24:9-160.
  2. Wong DL, Baker CM. Pain in children: comparison of assessment scales. Pediatr Nurs. 1988;14:9-17.
  3. Cuello García CA, Pérez Gaxiola G. La evidencia para el tratamiento de la cefalea y la migraña en niños y adolescentes sigue siendo limitada. Evid Pediatr. 2013;9:26.
  4. Togha M, Malamiri RA, Rashidi-Ranjbar N, Asa S, Mahvelati F, Ashrafi MR. Efficacy and safety of cinnarizine in the prophylaxis of migraine headaches in children: an open, randomized comparative trial with propranolol. Acta Neurol Belg. 2012;112:51-5.
  5. Damen L, Bruijn J, Verhagen AP, Berger MY, Passchier J, Koes BW. Prophylactic treatment of migrain in children. Part 2. A systematic review of pharmacological trials. Cephalalgia. 2006;26:497-505.
08/04/2015

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