June 2016. Volume 12. Number 2

Is nebulized magnesium useful in children with moderate and severe asthma attacks?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Alansari K, Ahmed W, Davidson BL, Alamri M, Zakaria I, Alrifaai M. Nebulized magnesium for moderate and severe pediatric asthma: A randomized trial. Pediatr Pulmonol. 2015;50:1191-9
Reviewers: Gimeno Díaz de Atauri Á1, Orejón de Luna G2.
1Servicio de Pediatría. Hospital 12 de Octubre. Madrid. España.
2CS General Ricardos. Madrid. España.
Correspondence: Álvaro Gimeno Díaz de Atauri. Email: agimenodatauri@gmail.com
Reception date: 18/03/2016
Acceptance date: 21/03/2016
Publication date: 30/03/2016

Abstract

Authors’ conclusions: adding nebulized magnesium to nebulized bronchodilator and systemic corticosteroids therapy does not shorten the time to discharge of pediatric patients with moderate or severe asthma in the Emergency Department.

Reviewers’ commentary: nebulized magnesium added to usual therapy does not improve outcomes in children with moderate and severe asthma in the Emergency Departments. Future research should focus on the subgroup of selected severe cases, in which previous studies have shown some benefit.

How to cite this article

Gimeno Díaz de Atauri A, Orejón de Luna G. En niños con crisis de asma moderadas o graves, ¿es útil el sulfato de magnesio nebulizado? Evid Pediatr. 2016;12:23.

AVC | Critically appraised articles

Alansari K, Ahmed W, Davidson BL, Alamri M, Zakaria I, Alrifaai M. Nebulized magnesium for moderate and severe pediatric asthma: A randomized trial. Pediatr Pulmonol. 2015;50:1191-9
Reviewers: Gimeno Díaz de Atauri Á1, Orejón de Luna G2.
1Servicio de Pediatría. Hospital 12 de Octubre. Madrid. España.
2CS General Ricardos. Madrid. España.
Correspondence: Álvaro Gimeno Díaz de Atauri. Email: agimenodatauri@gmail.com
Reception date: 18/03/2016
Acceptance date: 21/03/2016
Publication date: 30/03/2016

How to cite this article

Gimeno Díaz de Atauri A, Orejón de Luna G. En niños con crisis de asma moderadas o graves, ¿es útil el sulfato de magnesio nebulizado? Evid Pediatr. 2016;12:23.

References

  1. Ducharme FM, Chalut D, Plotnick L, Savdie C, Kudirka D, Zhang X, et al. The pediatric respiratory assessment measure: a valid clinical score for assessing acute asthma severity from toddlers to teenagers. J Pedatr. 2008;152:476-80.
  2. Powell C, Dwan K, Milan SJ, Beasley R, Hughes R, Knopp-Sihota JA, et al. Inhaled magnesium sulfate in the treatment of acute asthma. Cochrane Database Syst Rev. 2012;12:CD003898.
  3. Powell C, Kolamunnage-Dona R, Lowe J, Boland A, Petrou S, Doull I, Hood K, et al. MAGNEsium Trial In Children (MAGNETIC): a randomised, placebo-controlled trial and economic evaluation of nebulised magnesium sulphate in acute severe asthma in children. Health Technol Assess. 2013;17:1-216.
  4. Shan Z, Rong Y, Yang W, Wang D, Yao P, Xie J, et al. Intravenous and nebulized magnesium sulfate for treating acute asthma in adults and children: a systematic review and meta-analysis. Respir Med. 2013;107:321-30.
30/03/2016

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