March 2019. Volume 15. Number 1

The little remarkable protective effect of the probiotic on the atopic march probably does not remain in the long-term

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Wickens K, Barthow C, Mitchell EA, Kang J, van Zyl N, Purdie G, et al. Effects of Lactobacillus rhamnosus HN001 in early life on the cumulative prevalence of allergic disease to 11 years. Pediatr Allergy Immunol. 2018;29:808-814.

Reviewers: Molina Arias M1, Rivero Martín MJ2.
1Servicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
2Servicio de Pediatría. Hospital Universitario de Fuenlabrada. Fuenlabrada. Madrid. España.
Correspondence: Manuel Molina Arias. Email: mma1961@gmail.com
Reception date: 07/03/2019
Acceptance date: 15/03/2019
Publication date: 20/03/2019

Abstract

Author’s conclusions: beneficial effects of the combined pre- and post-natal intervention with the probiotic Lactobacillus rhamnosus HN001, regarding the protection against eczema, are maintained for at least the first decade of life, with possible extension to the atopic march.

Reviewers’ commentary: the results are not good enough to systematically recommend supplementation with probiotics for the prevention of the atopic march. The initial effect achieved is very limited and does not seem to be maintained in the long term.

How to cite this article

Molina Arias M, Rivero Martín MJ. La escasa prevención del probiótico sobre la marcha atópica probablemente no se mantiene a largo plazo. Evid Pediatr. 2019;15:3.

AVC | Critically appraised articles

Wickens K, Barthow C, Mitchell EA, Kang J, van Zyl N, Purdie G, et al. Effects of Lactobacillus rhamnosus HN001 in early life on the cumulative prevalence of allergic disease to 11 years. Pediatr Allergy Immunol. 2018;29:808-814.

Reviewers: Molina Arias M1, Rivero Martín MJ2.
1Servicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
2Servicio de Pediatría. Hospital Universitario de Fuenlabrada. Fuenlabrada. Madrid. España.
Correspondence: Manuel Molina Arias. Email: mma1961@gmail.com
Reception date: 07/03/2019
Acceptance date: 15/03/2019
Publication date: 20/03/2019

How to cite this article

Molina Arias M, Rivero Martín MJ. La escasa prevención del probiótico sobre la marcha atópica probablemente no se mantiene a largo plazo. Evid Pediatr. 2019;15:3.

20/03/2019

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