September 2019. Volume 15. Number 3

Has rotavirus vaccine unexpected benefits?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Hemming-Marlo M, Lähdeaho ML, Mäki M, Vesikari T. Rotavirus vaccination does not increase type 1 diabetes and may decrease celiac disease in children and adolescents. Pediatr Infect Dis J. 2019;38:539-41.

Reviewers: Fraile Astorga G1, Molina Arias M2.
1Pediatra. EAP Can Rull. Sabadell. Barcelona. España.
2Servicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
Correspondence: Garazi Fraile Astorga. Email: garazifraile@hotmail.com
Reception date: 10/09/2019
Acceptance date: 24/09/2019
Publication date: 02/10/2019

Abstract

Authors’ conclusions: rotavirus vaccination with live attenuated viruses did not alter the occurrence of diabetes mellitus type 1 but decreased the prevalence of celiac disease in childhood and adolescence. We propose that wild-type rotavirus may trigger celiac disease and the triggering effect can be prevented or reduced by rotavirus vaccination.

Reviewers’ commentary: rotavirus vaccine does not increase the risk of developing autoimmune diseases and it is even associated in this study with a decrease in the prevalence of celiac disease.

How to cite this article

Fraile Astorga G, Molina Arias M. ¿Tiene la vacunación frente al rotavirus beneficios inesperados? Evid Pediatr. 2019;15:30.

AVC | Critically appraised articles

Hemming-Marlo M, Lähdeaho ML, Mäki M, Vesikari T. Rotavirus vaccination does not increase type 1 diabetes and may decrease celiac disease in children and adolescents. Pediatr Infect Dis J. 2019;38:539-41.

Reviewers: Fraile Astorga G1, Molina Arias M2.
1Pediatra. EAP Can Rull. Sabadell. Barcelona. España.
2Servicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
Correspondence: Garazi Fraile Astorga. Email: garazifraile@hotmail.com
Reception date: 10/09/2019
Acceptance date: 24/09/2019
Publication date: 02/10/2019

How to cite this article

Fraile Astorga G, Molina Arias M. ¿Tiene la vacunación frente al rotavirus beneficios inesperados? Evid Pediatr. 2019;15:30.

02/10/2019

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