September 2020. Volume 16. Number 3

Statins seem to reduce the cardiovascular risk in children with inherited familial hypercholesterolemia

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Luirink IK, Wiegman A, Kusters DM, Hof MH, Groothoff JW, de Groot E, et al. 20-year follow-up of statins in children with familial hypercholesterolemia. N Engl J Med. 2019;381:1547-56.

Reviewers: Llerena Santa Cruz E1, Rodríguez-Salinas Pérez E2.
11Pediatra CAP La Torrassa. Hospital Parc Tauli. Sabadell. Barcelona. España.
2Pediatra. CS Colmenar Viejo Norte. Colmenar Viejo. Madrid. España.
Correspondence: Enrique Llerena Santa Cruz. Email: kikellerena@gmail.com
Reception date: 27/05/2020
Acceptance date: 02/06/2020
Publication date: 17/06/2020

Abstract

Authors’ conclusions: in patients with familial hypercholesterolemia statin treatment started in childhood reduces the tendency to thicken of the carotid intima-media and the risk of cardiovascular disease in adulthood.

Reviewers’ commentary: statin treatment since childhood could be safe and decrease the chances of having an event or death from cardiovascular disease. The data obtained on the thickness of the carotid intima-media cannot be extrapolated, nor can a relationship be established between these data and the results found in the study.

Key words: hydroxymethylglutaryl-CoA reductase inhibitors; cardiovascular diseases; hyperlipoproteinemia type II; carotid intima-media thickness.

How to cite this article

Llerena Santa Cruz E, Rodríguez-Salinas Pérez E. Las estatinas parecen disminuir el riesgo cardiovascular en niños con hipercolesterolemia familiar hereditaria. Evid Pediatr. 2020;16:29.

AVC | Critically appraised articles

Luirink IK, Wiegman A, Kusters DM, Hof MH, Groothoff JW, de Groot E, et al. 20-year follow-up of statins in children with familial hypercholesterolemia. N Engl J Med. 2019;381:1547-56.

Reviewers: Llerena Santa Cruz E1, Rodríguez-Salinas Pérez E2.
11Pediatra CAP La Torrassa. Hospital Parc Tauli. Sabadell. Barcelona. España.
2Pediatra. CS Colmenar Viejo Norte. Colmenar Viejo. Madrid. España.
Correspondence: Enrique Llerena Santa Cruz. Email: kikellerena@gmail.com
Reception date: 27/05/2020
Acceptance date: 02/06/2020
Publication date: 17/06/2020

How to cite this article

Llerena Santa Cruz E, Rodríguez-Salinas Pérez E. Las estatinas parecen disminuir el riesgo cardiovascular en niños con hipercolesterolemia familiar hereditaria. Evid Pediatr. 2020;16:29.

17/06/2020

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