March 2022. Volume 18. Number 1

Is it possible to use in children a shorter 3-day duration treatment for community acquired pneumonia?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Bielicki JA, Stöhr W, Barratt S, Dunn D, Naufal N, Roland D, et al. Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial. JAMA. 2021;326:1713-24.
Reviewers: Ruiz-Canela Cáceres J1, Pérez-Moneo Agapito B2.
1Pediatra. Grupo de Pediatría Basada en la Evidencia. Sevilla. España.
2Servicio de Pediatría. Hospital Universitario Infanta Leonor. Universidad Complutense de Madrid. Madrid. España.
Correspondence: Juan Ruiz-Canela Cáceres. Email: jruizcanela@gmail.com
Reception date: 25/01/2022
Acceptance date: 10/02/2022
Publication date: 23/02/2022

Abstract

Authors‘ conclusions: among children with community acquired pneumonia discharged from an emergency department or hospital ward (within 48 hours), lower-dose outpatient oral amoxicillin was non inferior to higher dose, and 3-day duration was non inferior to 7 days, with regard to need for antibiotic re-treatment.

Reviewers‘ conclusions: the data from this study invite us to review in our environment the guidelines used in children in the treatment of pneumonia in the community, with the purpose of clarifying if the shorter duration of treatment and lower dosage could lead to benefits, but there are limitations in the study for its conclusions to be applicable in our country.

How to cite this article

Ruiz-Canela Cáceres J, Pérez-Moneo Agapito B. En niños ¿se puede acortar el tratamiento de la neumonía adquirida en la comunidad a 3 días? Evid Pediatr. 2022;18:7.

AVC | Critically appraised articles

Bielicki JA, Stöhr W, Barratt S, Dunn D, Naufal N, Roland D, et al. Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial. JAMA. 2021;326:1713-24.
Reviewers: Ruiz-Canela Cáceres J1, Pérez-Moneo Agapito B2.
1Pediatra. Grupo de Pediatría Basada en la Evidencia. Sevilla. España.
2Servicio de Pediatría. Hospital Universitario Infanta Leonor. Universidad Complutense de Madrid. Madrid. España.
Correspondence: Juan Ruiz-Canela Cáceres. Email: jruizcanela@gmail.com
Reception date: 25/01/2022
Acceptance date: 10/02/2022
Publication date: 23/02/2022

How to cite this article

Ruiz-Canela Cáceres J, Pérez-Moneo Agapito B. En niños ¿se puede acortar el tratamiento de la neumonía adquirida en la comunidad a 3 días? Evid Pediatr. 2022;18:7.

23/02/2022

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