March 2023. Volume 19. Number 1

Antibiotics appear to reduce induced humoral immunogenicity in children under 2 years of age

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Chapman TJ, Pham M, Bajorski P, Pichichero ME. Antibiotic use and vaccine antibody levels. Pediatrics. 2022;149: e2021052061.

Reviewers: Rodríguez-Salinas Pérez E1, Balado Insunza MN2.
1Pediatra. CS Colmenar Viejo Norte. Colmenar Viejo. Madrid. España.
2Servicio de Pediatría. Hospital Álvaro Cunqueiro. Vigo. Pontevedra. España.
Correspondence: Enrique Rodríguez-Salinas Pérez. Email: erodriguez-salinas@pap.es
Reception date: 29/12/2022
Acceptance date: 09/01/2023
Publication date: 18/01/2023

Abstract

Authors´ conclusions: there is a decrease in the antibody response to main vaccines by consumption of antibiotics in children under two years.

Reviewers´ commentary: the results described warn of the possible lower effect of vaccines in children who use antibiotics too frequently. Until now it has not been proven that the observed reduction in antibody levels is accompanied by the development of diseases preventable by these vaccines.

How to cite this article

Rodríguez-Salinas Pérez E, Balado Insunza N. Los antibióticos parecen reducir la inmunogenicidad humoral inducida en menores de 2 años. Evid Pediatr. 2023;19:3.

AVC | Critically appraised articles

Chapman TJ, Pham M, Bajorski P, Pichichero ME. Antibiotic use and vaccine antibody levels. Pediatrics. 2022;149: e2021052061.

Reviewers: Rodríguez-Salinas Pérez E1, Balado Insunza MN2.
1Pediatra. CS Colmenar Viejo Norte. Colmenar Viejo. Madrid. España.
2Servicio de Pediatría. Hospital Álvaro Cunqueiro. Vigo. Pontevedra. España.
Correspondence: Enrique Rodríguez-Salinas Pérez. Email: erodriguez-salinas@pap.es
Reception date: 29/12/2022
Acceptance date: 09/01/2023
Publication date: 18/01/2023

How to cite this article

Rodríguez-Salinas Pérez E, Balado Insunza N. Los antibióticos parecen reducir la inmunogenicidad humoral inducida en menores de 2 años. Evid Pediatr. 2023;19:3.

18/01/2023

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