December 2023. Volume 19. Number 4

Vaccinating pregnant women can prevent respiratory syncytial virus bronchiolitis in infants

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Kampmann B, Madhi SA, Munjal I, Simões EAF, Pahud BA, Llapur C, et al. Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants. N Engl J Med. 2023;388:1451-64.

Reviewers: Ochoa Sangrador C1, Rodríguez-Salinas Pérez E2.
1Servicio de Pediatría. Complejo Asistencial de Zamora. Zamora. España.
2Pediatra. CS Colmenar Viejo Norte. Colmenar Viejo. Madrid. España.
Correspondence: Carlos Ochoa Sangrador. Email: cochoas2@gmail.com
Reception date: 20/09/2023
Acceptance date: 17/10/2023
Publication date: 25/10/2023

Abstract

Authors´ conclusions: prefusion F protein vaccine against respiratory syncytial virus administered to pregnant women in the last trimester of pregnancy prevents this virus severe respiratory infections in their infants, without important adverse effects.

Reviewers´ commentary: the vaccine appears effective and safe, although its efficacy estimates are imprecise. It constitutes an alternative preventive option to the administration of nirsevimab in the newborn, with comparable impact expectations.

How to cite this article

Ochoa Sangrador C, Rodríguez-Salinas Pérez E. Vacunar a la embarazada puede prevenir la bronquiolitis por virus respiratorio sincitial en el lactante. Evid Pediatr. 2023;19:40.

AVC | Critically appraised articles

Kampmann B, Madhi SA, Munjal I, Simões EAF, Pahud BA, Llapur C, et al. Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants. N Engl J Med. 2023;388:1451-64.

Reviewers: Ochoa Sangrador C1, Rodríguez-Salinas Pérez E2.
1Servicio de Pediatría. Complejo Asistencial de Zamora. Zamora. España.
2Pediatra. CS Colmenar Viejo Norte. Colmenar Viejo. Madrid. España.
Correspondence: Carlos Ochoa Sangrador. Email: cochoas2@gmail.com
Reception date: 20/09/2023
Acceptance date: 17/10/2023
Publication date: 25/10/2023

How to cite this article

Ochoa Sangrador C, Rodríguez-Salinas Pérez E. Vacunar a la embarazada puede prevenir la bronquiolitis por virus respiratorio sincitial en el lactante. Evid Pediatr. 2023;19:40.

25/10/2023

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