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Evidencias en Pediatría (EP / Evidences in Pediatrics) is a publication of the “Asociación Española de Pediatría” (AEP / Spanish Association of Pediatrics). Its contents are elaborated mainly by members of the Grupo de Trabajo de Pediatría Basada en la Evidencia (Evidence Based Pediatrics Working Group). This group is part of both, the AEP and the “Asociación Española de Pediatría de Atención Primaria” (Spanish Association of Primary Care Pediatrics / AEPap).
Authors' conclusions: ondansetron therapy decreases the risk of persistent vomiting, hospital admissions and the use of intravenous fluid, in children with vomiting due to gastroenteritis. Treatment guidelines should incorporate ondansetron for the therapy of selected childrens with gastroenteritis.
Reviewers' comantary: despite the fact that ondansetron appears to reduce the vomiting of patients with gastroenteritis, the information provided by this review does not clear up some doubts that question its widespread application in clinical practice. It would be necessary to conduct more studies that include a broader spectrum of patients and evaluating the benefit of treatment on the patient.
Alhashimi D, Alhashimi H, Fedorowicz Z. Antieméticos para reducir los vómitos relacionados con la gastroenteritis aguda en niños y adolescentes (Revisión Cochrane traducida). En: La Biblioteca Cochrane Plus, 2008 Número 2. Oxford: Update Software Ltd. Disponible en: http://www.update-software.com. (Traducida de The Cochrane Library, 2008 Issue 2. Chichester, UK: John Wiley & Sons, Ltd.).