March 2009. Volume 5. Number 1

The use of paracetamol in the first years of life can be associated with a greater incidence of allergic disease (asthma, rhynoconjuntivitis and dermatitis)

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Beasley R, Clayton T, Crane J, von Mutis E, K W Lai C, Montefort S et al. Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjuntivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programme. Lancet. 2008;372:1039-48
Reviewers: Perdikidis Olivieri L1, Fernández Rodríguez M2.
1EAP Juncal. Torrejón de Ardoz. Madrid. España.
2Centro de Salud de Potes. Madrid. España.
Correspondence: Leo Perdikidis Olivieri. Email: lperdikidis@gmail.com
Reception date: 04/02/2009
Acceptance date: 12/02/2009
Publication date: 21/02/2009

Abstract

Authors' conclusions: the use of paracetamol in infancy can be a risk factor for asthma,rhynoconjuntivitis and eczema.

Reviewers' comantary: the most important limitations of this study are its retrospective nature, and the not corrected selection byass: the analysis adjusted for confusion factors was undertaken in 51% of the study population and no information was given whether this subgroup had differences with the population of origin. The study supports the conclusions of other authors about paracetamol as a possible risk factor although new studies are necessary to confirm or discard the rol of paracetamol in the development of allergic disease.

How to cite this article

Perdikidis Olivieri L, Fernández Rodríguez M. El consumo de paracetamol en los primeros años de vida se puede asociar a mayor patología alérgica (asma, rinoconjuntivitis y dermatitis). Evid Pediatr. 2009;5:22.

AVC | Critically appraised articles

Beasley R, Clayton T, Crane J, von Mutis E, K W Lai C, Montefort S et al. Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjuntivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programme. Lancet. 2008;372:1039-48
Reviewers: Perdikidis Olivieri L1, Fernández Rodríguez M2.
1EAP Juncal. Torrejón de Ardoz. Madrid. España.
2Centro de Salud de Potes. Madrid. España.
Correspondence: Leo Perdikidis Olivieri. Email: lperdikidis@gmail.com
Reception date: 04/02/2009
Acceptance date: 12/02/2009
Publication date: 21/02/2009

How to cite this article

Perdikidis Olivieri L, Fernández Rodríguez M. El consumo de paracetamol en los primeros años de vida se puede asociar a mayor patología alérgica (asma, rinoconjuntivitis y dermatitis). Evid Pediatr. 2009;5:22.

References

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21/02/2009

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