July 2009. Volume 5. Number 2

There´s no evidence to support therapies in preventing or treating renal disease in Henoch-Schönlein purpura

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Chartapisak W, Opastiraku SL, Willis NS, Craig JC, Hodson EM. Prevention and treatment of renal disease in Henoch-Schönlein purpura: a systematic review. Arch Dis Child. 2009;94:132-7
Reviewers: González de Dios J1, Rivas Juesas C2.
1Departamento de Pediatría. Hospital General Universitario de Alicante. España.
2Servicio de Pediatría. Hospital de Sagunto. Valencia. España.
Correspondence: Javier González de Dios. Email: javier.gonzalezdedios@gmail.com
Reception date: 30/04/2009
Acceptance date: 04/05/2009
Publication date: 01/06/2009

Abstract

Authors' conclusions: nowadays there is no evidence to use drug therapies in preventing or treating renal disease in Henoch-Schönlein purpura (SHP).

Reviewers´ commentary: there is no evidence to prescribe corticoids at the beginning of SHP in preventing persistent renal disease, neither to treat severe nephritis with inmunossupresors. Results about the use of steroids contradict the conclusions of a previous systematic review, based on poor quality trials

How to cite this article

González de Dios J, Rivas Juesas C. No existe evidencia actualmente que apoye el uso de ninguna intervención para prevenir o tratar el daño renal de la púrpura de Schönlein-Henoch. Evid Pediatr. 2009;5:38.

AVC | Critically appraised articles

Chartapisak W, Opastiraku SL, Willis NS, Craig JC, Hodson EM. Prevention and treatment of renal disease in Henoch-Schönlein purpura: a systematic review. Arch Dis Child. 2009;94:132-7
Reviewers: González de Dios J1, Rivas Juesas C2.
1Departamento de Pediatría. Hospital General Universitario de Alicante. España.
2Servicio de Pediatría. Hospital de Sagunto. Valencia. España.
Correspondence: Javier González de Dios. Email: javier.gonzalezdedios@gmail.com
Reception date: 30/04/2009
Acceptance date: 04/05/2009
Publication date: 01/06/2009

How to cite this article

González de Dios J, Rivas Juesas C. No existe evidencia actualmente que apoye el uso de ninguna intervención para prevenir o tratar el daño renal de la púrpura de Schönlein-Henoch. Evid Pediatr. 2009;5:38.

References

  1. Wyatt RJ, Hogg RJ. Evidence-based assessment of treatment options for children with IgA nephropathies. Pediatr Nephrol. 2001;16:156-67.
  2. Zaffanello M, Brugnara M, Franchini M. Therapy for children with henoch-schonlein purpura nephritis: a systematic review. ScientificWorldJournal. 2007;7:20-30.
  3. Weiss PF, Feinstein JA, Luan X, Burnham JM, Feudtner C. Effects of corticosteroid on Henoch-Schönlein purpura: a systematic review. Pediatrics. 2007;120:1079-87.
  4. Chalco Orrego JP, Bada Mancilla CA, Rojas Galarza RA. ¿Debemos utilizar corticoides sistémicos de forma precoz en niños con Púrpura de Henoch-Schönlein para disminuir el riesgo de desarrollo de enfermedad renal persistente? Evid Pediatr. 2008;4:14.
01/06/2009

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