June 2012. Volume 8. Number 2

Gastroesophageal reflux: proton pump inhibitors do not improve symptoms in infants

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Chen IL, Gao WY, Johnson AP, Niak A, Troiani J, Korvick J et al. Proton pump inhibitor use in infants: FDA reviewer experience. J Pediatr Gastroenterol Nutr. 2012;54(1):8-14.
Reviewers: Cuestas Montañés E1, Ortega Páez E2.
1Servicio de Pediatría y Neonatología. Hospital Privado. Centro Formador. Facultad de Ciencias Médicas. Universidad Nacional de Córdoba. Córdoba. Argentina.
2CS Maracena. Distrito metropolitano. Granada. España.
Correspondence: Eduardo José Cuestas Montañés. Email: eduardo.cuestas@gmail.com
Reception date: 03/05/2012
Acceptance date: 11/05/2012
Publication date: 23/05/2012

Abstract

Authors' conclusions: proton pump inhibitors (PPI’s) should not be administrated to treat the symptoms of  gastroesophageal reflux disease (GERD) in otherwise clinically healthy infants without the evidence of acid-induced disease.

Reviewers' commentary: although PPIs have been shown to increase gastric pH in these trials, there is currently no evidence of its efficacy in treating symptoms of gastroesophageal reflux in patients from one to twelve months old, consequently they are not recommended.

How to cite this article

Ortega Páez E, Cuestas Montañés E. Reflujo gastroesofágico: los inhibidores de la bomba de protones no mejoran la sintomatología en lactantes. Evid Pediatr. 2012;8:39.

AVC | Critically appraised articles

Chen IL, Gao WY, Johnson AP, Niak A, Troiani J, Korvick J et al. Proton pump inhibitor use in infants: FDA reviewer experience. J Pediatr Gastroenterol Nutr. 2012;54(1):8-14.
Reviewers: Cuestas Montañés E1, Ortega Páez E2.
1Servicio de Pediatría y Neonatología. Hospital Privado. Centro Formador. Facultad de Ciencias Médicas. Universidad Nacional de Córdoba. Córdoba. Argentina.
2CS Maracena. Distrito metropolitano. Granada. España.
Correspondence: Eduardo José Cuestas Montañés. Email: eduardo.cuestas@gmail.com
Reception date: 03/05/2012
Acceptance date: 11/05/2012
Publication date: 23/05/2012

How to cite this article

Ortega Páez E, Cuestas Montañés E. Reflujo gastroesofágico: los inhibidores de la bomba de protones no mejoran la sintomatología en lactantes. Evid Pediatr. 2012;8:39.

References

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23/05/2012

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