December 2015. Volume 11. Number 4

Influenza vaccination is associated with a weak increase in the risk of Guillain-Barré syndrome

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Martín Arias LH, Sanz R, Sáinz M, Treceño C, Carvajal A. Guillain-Barré syndrome and influenza vaccines: a meta-analysis. Vaccine. 2015;33:3773-8.
Reviewers: Ruiz-Canela Cáceres J1, Fernández Rodríguez M2.
1CS Virgen de África. Sevilla. España.
2CS Potes. Madrid. España.
Correspondence: Juan Ruiz-Canela Cáceres. Email: jruizcanela@gmail.com
Reception date: 04/11/2015
Acceptance date: 14/11/2015
Publication date: 18/11/2015

Abstract

Authors' conclusions: the vaccine anti-influenza A/H1N1 has a weak association with the development of Guillain-Barré syndrome.

Reviewers' commentary:despite the limitations of the present study, the results should be considered in adopting an individual decision on vaccination. However, the risk of Guillain-Barré syndrome after vaccination must be weighed against the proven benefits of the vaccination and the resulting reduction in influenza-related complications.

How to cite this article

Ruiz-Canela Cáceres J, Fernández Rodríguez M. La vacunación antigripal se asocia con un débil aumento del riesgo de síndrome de Guillain Barré. Evid Pediatr. 2015;11:65.

AVC | Critically appraised articles

Martín Arias LH, Sanz R, Sáinz M, Treceño C, Carvajal A. Guillain-Barré syndrome and influenza vaccines: a meta-analysis. Vaccine. 2015;33:3773-8.
Reviewers: Ruiz-Canela Cáceres J1, Fernández Rodríguez M2.
1CS Virgen de África. Sevilla. España.
2CS Potes. Madrid. España.
Correspondence: Juan Ruiz-Canela Cáceres. Email: jruizcanela@gmail.com
Reception date: 04/11/2015
Acceptance date: 14/11/2015
Publication date: 18/11/2015

How to cite this article

Ruiz-Canela Cáceres J, Fernández Rodríguez M. La vacunación antigripal se asocia con un débil aumento del riesgo de síndrome de Guillain Barré. Evid Pediatr. 2015;11:65.

References

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  3. Baxter R, Bakshi N, Fireman B, Lewis E, Ray P, Vellozzi C, et al. Lack of association of Guillain-Barre syndrome with vaccinations. Clin Infect Dis. 2013;57:197-204.
  4. Salmon DA, Proschan M, Forshee R, Gargiullo P, Bleser W, Burwen DR, et al. Association between Guillain-Barré syndrome and influenza A (H1N1) 2009 monovalent inactivated vaccines in the USA: a meta-analysis. Lancet. 2013;381:1461-8.
  5. Dodd CN, Romio SA, Black S, Vellozzi C, Andrews N, Sturkenboom M, et al. International collaboration to assess the risk of Guillain Barré Syndrome following Influenza A (H1N1) 2009 monovalent vaccines. Vaccine. 2013 40:4448-58.
18/11/2015

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