September 2016. Volume 12. Number 3

The early introduction of food in babies with breastfeeding does not prevent food allergy

 
 
 
 
 
 
 
 
 
 
Rating: 3 (1 Votes)
Newsletter Free Subscription
Regularly recieve most recent articles by e-mail
Subscribe
Print
Add to library
Discuss this article

AVC | Critically appraised articles

Perkin MR, Logan K, Tseng A, Raji B, Ayis S, Peacock J, et al. Randomized trial of introduction of allergenic foods in breast fed infants. N Engl J Med. 2016;374:1733-43.
Reviewers: Fernández Rodríguez M1, Martín-Crespo Blanco C2.
1CS Potes. Madrid. España.
2Hospital Universitario Infantil Niño Jesús. Madrid. España.
Correspondence: Mercedes Fernández Rodríguez. Email: mer763@hotmail.com
Reception date: 19/09/2016
Acceptance date: 23/09/2016
Publication date: 28/09/2016

Abstract

Authors´ conclusions: the study did not show the efficiency of the early introduction of allergenic foods in the analysis for intention of treating, but analyzing only the cases that completed the protocol the prevention of the food allergy is a dependent dose.

Reviewers´ commentary: this study no significant limitations on the validity, although losses and lack of adherence to the protocol could influence an underestimation of the effect. The early introduction of potentially allergenic foods in breastfed infants without risk of allergy, does not seem to have a protective effect for the development of food allergy.

How to cite this article

Fernández Rodríguez M, Martín-Crespo Blanco MC. La introducción precoz de alimentos en lactantes con lactancia materna aparentemente no previene la alergia alimentaria. Evid Pediatr. 2016;12:49.

AVC | Critically appraised articles

Perkin MR, Logan K, Tseng A, Raji B, Ayis S, Peacock J, et al. Randomized trial of introduction of allergenic foods in breast fed infants. N Engl J Med. 2016;374:1733-43.
Reviewers: Fernández Rodríguez M1, Martín-Crespo Blanco C2.
1CS Potes. Madrid. España.
2Hospital Universitario Infantil Niño Jesús. Madrid. España.
Correspondence: Mercedes Fernández Rodríguez. Email: mer763@hotmail.com
Reception date: 19/09/2016
Acceptance date: 23/09/2016
Publication date: 28/09/2016

How to cite this article

Fernández Rodríguez M, Martín-Crespo Blanco MC. La introducción precoz de alimentos en lactantes con lactancia materna aparentemente no previene la alergia alimentaria. Evid Pediatr. 2016;12:49.

References

  1. Cuestas Montañés E, Ortega Páez E. La introducción precoz de alimentos potencialmente alergénicos no parece relacionarse con el riesgo de tener sibilancias o eccema. Evid Pediatr. 2012;8:16.
  2. Du Toit G, Sayre PH, Roberts G, Sever ML, Lawson K, Bahnson HT, et al. Immune tolerance network LEAP-On study team. Effect of avoidance on peanut allergy after early peanut consumption. N Engl J Med. 2016;374:1435-43.
  3. Palmer DJ1, Metcalfe J, Makrides M, Gold MS, Quinn P, West CE, et al. Early regular egg exposure in infants with eczema: A randomized controlled trial. J Allergy Clin Immunol. 2013;132:387-92.
  4. Muraro A, Halken S, Arshad SH, Beyer K, Dubois AE, Du Toit G, et al. EAACI food allergy and anaphylaxis guidelines. Primary prevention of food allergy. Allergy. 2014;69:590-601
  5. Fleischer DM, Spergel JM, Assa'ad AH, Pongracic JA. Primary prevention of allergic disease through nutritional interventions. J Allergy Clin Immunol Pract. 2013;1:29-36.
28/09/2016

Linked Comment