October 2010. Volume 6. Number 3

Flu vaccine can be administered safely following a split dose vaccination protocol in children allergic to egg without risk of severe adverse reactions

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Chung EY, Huang L, Schneider L. Safety of influenza vaccine administration in egg-allergic patients. Pediatrics. 2010;125(5):e1024-30.
Reviewers: Buñuel Álvarez JC1, González de Dios J2.
1Àrea Bàsica de Salut Girona-4. Institut Català de la Salut. Girona. España.
2Departamento de Pediatría. Hospital General Universitario de Alicante. España.
Correspondence: José Cristóbal Buñuel Álvarez. Email: jcbunuel@gmail.com
Reception date: 12/07/2010
Acceptance date: 15/07/2010
Publication date: 20/07/2010

Abstract

Authors’ conclusions: In children with egg allergy without history of anaphylaxis influenza vaccine may be administered in two divided doses with no need for a prior prick test with vaccine antigen.

Reviewers’ commentary: With currently available data from observational and experimental studies, it is concluded that administration of influenza vaccine is safe in children with egg allergy without anaphylaxis.

How to cite this article

Buñuel Álvarez JC, González de Dios J. En niños alérgicos al huevo puede administrarse la vacuna antigripal de forma fraccionada sin riesgo de reacción adversa grave. Evid Pediatr. 2010;6:49.

AVC | Critically appraised articles

Chung EY, Huang L, Schneider L. Safety of influenza vaccine administration in egg-allergic patients. Pediatrics. 2010;125(5):e1024-30.
Reviewers: Buñuel Álvarez JC1, González de Dios J2.
1Àrea Bàsica de Salut Girona-4. Institut Català de la Salut. Girona. España.
2Departamento de Pediatría. Hospital General Universitario de Alicante. España.
Correspondence: José Cristóbal Buñuel Álvarez. Email: jcbunuel@gmail.com
Reception date: 12/07/2010
Acceptance date: 15/07/2010
Publication date: 20/07/2010

How to cite this article

Buñuel Álvarez JC, González de Dios J. En niños alérgicos al huevo puede administrarse la vacuna antigripal de forma fraccionada sin riesgo de reacción adversa grave. Evid Pediatr. 2010;6:49.

References

  1. James JM, Zeiger RS, Lester MR, Fasano MB, Gern JE, Mansfield LE et al. Safe administration of influenza vaccine to patients with egg allergy. J Pediatr. 1998;133:624-8.
  2. Esposito S, Gasparini C, Martelli A, Zenga A, Tremolati E, Varin E et al. Safe administration of an inactivated virosomal adjuvanted influenza vaccine in asthmatic children with egg allergy. Vaccine. 2008;26:4664-8.
  3. Ministerio de Sanidad y Política Social. Protocolo de actuación en casos de gripe pandémica (H1N1) 2009 en Pediatría [consultado 2 de julio de 2010]. Disponible en: http://www.msps.es/profesionales/saludPublica/gripeA/guiasProtocolosInf/pdf/14Dic09Pediatria.pdf
20/07/2010

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