December 2014. Volume 10. Number 4

Broad-spectrum antibiotics do not improve the treatment of community acquired pneumonia.

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Queen MA, Myers AL, Hall M, Shah SS, Williams DJ, Auger KA, et al. Comparative effectiveness of empiric antibiotics for community-acquired pneumonia. Pediatrics. 2014;133:e23-9.
Reviewers: Francisco González L1, Ochoa Sangrador C2.
1Hospital Clínico San Carlos. Madrid. España.
2Servicio de Pediatría. Hospital Virgen de la Concha. Zamora. España.
Correspondence: Laura Francisco González. Email: laura.francisco.gonzalez@gmail.com
Reception date: 15/09/2014
Acceptance date: 19/09/2014
Publication date: 01/10/2014

Abstract

Authors' conclusions: compared with broad-spectrum agents, narrow-spectrum antibiotic coverage is associated with similar outcomes. Our findings support national consensus recommendations for the use of narrow-spectrum antibiotics in children hospitalized with Community Acquired Pneumonia.

Reviewers' commentary: the use of broad spectrum antibiotics is not related to benefits in the hospital admission for community- acquired pneumonia. However, the longer hospital stay observed in these patients could be due to no adjusted basal risk differences. Although the recommendation for using narrow spectrum antibiotics is more rational in the beginning, only the development of an experimental study would let estimate its impact.

How to cite this article

Francisco González L, Ochoa Sangrador C. Los antibióticos de amplio espectro no mejoran el tratamiento de la neumonía comunitaria. Evid. Pediatr. 2014;10:65.

AVC | Critically appraised articles

Queen MA, Myers AL, Hall M, Shah SS, Williams DJ, Auger KA, et al. Comparative effectiveness of empiric antibiotics for community-acquired pneumonia. Pediatrics. 2014;133:e23-9.
Reviewers: Francisco González L1, Ochoa Sangrador C2.
1Hospital Clínico San Carlos. Madrid. España.
2Servicio de Pediatría. Hospital Virgen de la Concha. Zamora. España.
Correspondence: Laura Francisco González. Email: laura.francisco.gonzalez@gmail.com
Reception date: 15/09/2014
Acceptance date: 19/09/2014
Publication date: 01/10/2014

How to cite this article

Francisco González L, Ochoa Sangrador C. Los antibióticos de amplio espectro no mejoran el tratamiento de la neumonía comunitaria. Evid. Pediatr. 2014;10:65.

References

  1. Montejo M, González C, Mintegi S, Benito J. Estudio clínico y epidemiológico de la neumonía adquirida en la comunidad en niños menores de 5 años de edad. An Pediatr (Barc). 2005;63:131-6.
  2. Bradley JS, Byington CL, Shah SS, Alverson B, Carter ER, Harrison C, et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practiceguidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011;53:e25-76.
  3. Dinur-Schejter Y, Cohen-Cymberknoh M, Tenenbaum A, Brooks R, Averbuch D, Kharasch S, et al. Antibiotic treatment of children with community-acquired pneumonia: comparison of penicillin or ampicillin versus cefuroxime. Pediatr Pulmonol. 2013;48:52-8.
01/10/2014

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