June 2025. Volume 21. Number 2

Salbutamol in mild asthmatic exacerbations in children. Three is not better than one

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Özdemir A, Ersoy M, Aydoğdu AK. Once or consecutive administration of inhaled salbutamol in children with acute asthma exacerbation: Is an additional dose beneficial? Pediatr Pulmonol. 2024;59(12):3190-6.

Reviewers: Gimeno Díaz de Atauri Á1, Espínola Docio B2.
1Sección de Neumología y Alergia Infantil. Servicio de Pediatría. Hospital Universitario 12 de Octubre. Madrid. España.
2Pediatra. CS Los Alperchines. San Fernando de Henares. Madrid. España.
Correspondence: Álvaro Gimeno Díaz de Atauri. Email: agimenodatauri@gmail.com
Reception date: 19/05/2025
Acceptance date: 28/05/2025
Publication date: 11/06/2025

Abstract

Authors´ conclusions: the bronchodilator effect of a single inhaled dose of short action beta agonists with a valve holding chamber is similar to the administration of successive doses in children with mild acute asthma exacerbation.

Reviewers’ commentary: this study in children with mild asthmatic exacerbations, after a first effective dose of salbutamol, finds no short-term functional benefit in administering successive doses. There is no evidence in the longer term impact or in other clinical variables. There is no data about the effect in more severe exacerbations neither in patients with partial response to a first dose of bronchodilator.

How to cite this article

Gimeno Díaz de Atauri A, Espínola Docio B. Salbutamol en exacerbaciones asmáticas leves en niños. Tres no es mejor que uno. Evid Pediatr. 2025;21:20.

AVC | Critically appraised articles

Özdemir A, Ersoy M, Aydoğdu AK. Once or consecutive administration of inhaled salbutamol in children with acute asthma exacerbation: Is an additional dose beneficial? Pediatr Pulmonol. 2024;59(12):3190-6.

Reviewers: Gimeno Díaz de Atauri Á1, Espínola Docio B2.
1Sección de Neumología y Alergia Infantil. Servicio de Pediatría. Hospital Universitario 12 de Octubre. Madrid. España.
2Pediatra. CS Los Alperchines. San Fernando de Henares. Madrid. España.
Correspondence: Álvaro Gimeno Díaz de Atauri. Email: agimenodatauri@gmail.com
Reception date: 19/05/2025
Acceptance date: 28/05/2025
Publication date: 11/06/2025

How to cite this article

Gimeno Díaz de Atauri A, Espínola Docio B. Salbutamol en exacerbaciones asmáticas leves en niños. Tres no es mejor que uno. Evid Pediatr. 2025;21:20.

11/06/2025

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