October 2011. Volume 7. Number 3

Malaria during pregnancy increases infant morbidity and mortality

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Bardají A, Sigauque B, Sanz S, Maixenchs M, Ordi J, Aponte JJ et al. Impact of malaria at the end of pregnancy on infant mortality and morbidity. J Infect Dis. 2011:203:691-99.
Reviewers: Bonillo Perales A1, Perdikidis Olivieri L2.
1Hospital Torrecárdenas. Almería. España.
2EAP Juncal. Torrejón de Ardoz. Madrid. España.
Correspondence: Antonio Bonillo Perales. Email: abonillop@gmail.com
Reception date: 11/04/2011
Acceptance date: 23/06/2011
Publication date: 29/06/2011

Abstract

Authors' conclusions: malaria infection at the end of pregnancy and maternal clinical malaria negatively impact survival and malaria morbidity in infancy. Effective clinical management and prevention of malaria in pregnancy may improve infant´s health and survival.

Reviewers' commentary: children of women with malaria during pregnancy, acute placental infection and cord infection have a higher infant mortality and an increased risk of malaria infection during the first year of life. Thus, it seems appropriate to initiate preventive measures against malaria during pregnancy, but further studies are needed to identify the most effective.

How to cite this article

Bonillo Perales A, Perdikidi Olivieri L. La malaria durante el embarazo aumenta la morbimortalidad infantil. Evid Pediatr. 2011;7:60.

AVC | Critically appraised articles

Bardají A, Sigauque B, Sanz S, Maixenchs M, Ordi J, Aponte JJ et al. Impact of malaria at the end of pregnancy on infant mortality and morbidity. J Infect Dis. 2011:203:691-99.
Reviewers: Bonillo Perales A1, Perdikidis Olivieri L2.
1Hospital Torrecárdenas. Almería. España.
2EAP Juncal. Torrejón de Ardoz. Madrid. España.
Correspondence: Antonio Bonillo Perales. Email: abonillop@gmail.com
Reception date: 11/04/2011
Acceptance date: 23/06/2011
Publication date: 29/06/2011

How to cite this article

Bonillo Perales A, Perdikidi Olivieri L. La malaria durante el embarazo aumenta la morbimortalidad infantil. Evid Pediatr. 2011;7:60.

References

  1. Menéndez C, Bardaji A, Sigauque B, Romagosa C, Sanz S, Serra-Casas E et al. A randomized placebo controlled trial of intermittent preventive treatment in pregnant women in the context of insecticide treated nets delivered through the antenatal clinic. PLoS One. 2008;3: e1934.
  2. Nyirjesy P, Kavasya T, Axelrod P, Fischer PR. Malaria during pregnancy:neonatal morbidity and mortality and the efficacy of chloroquine chemoprophylaxis. Clin Infect Dis. 1993;16:127-32.
  3. Bloland PB, Wirima JJ, Steketee RW, Chilima B, Hightower A, Breman JG. Maternal HIV infection and infant mortality in Malawi:evidence for increased mortality due to placental malaria infection. AIDS. 1995;9:721-6.
  4. Menenedez C, Bardají A, Sigauque B, Sanz S, Aponte JJ, Mabunda S et al. Malaria prevention with IPTp during pregnancy reduces neonatal mortality. Plos One. 2010;5:e9438.
  5. Haghdoost AA, Alexander N, Smith T. Maternal malaria during pregnancy and infantmortality rate: critical literature review and a new analytical approach. J Vector Borne Dis. 2007;44:98-104.
  6. Sacarlal J, Lafuente S, Macete E, Alonso PL. Últimos avances en el desarrollo de una vacuna de la malaria. Evid Pediatr. 2008;4:2.
29/06/2011

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