March 2013. Volume 9. Number 1

Severe neonatal hyperbilirubinemia without significant early encephalopathy does not affect children’s development

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Vandborg PK, Hansen BM, Greisen G, Jepsen M, Ebbesen F. Follow-up of neonates with total serum bilirubin levels ≥ 25 mg/dL: a Danish population-based study. Pediatrics. 2012;130:61-6.
Reviewers: Aparicio Rodrigo M1, Aparicio Sánchez JL2.
1Centro de Salud Entreví­as. Área 1. Madrid. España.
2Servicio de Pediatría. Hospital Dr. José Molina Orosa. Lanzarote. Las Palmas. España.
Correspondence: María Aparicio Rodrigo. Email: maparicio@salud.madrid.org
Reception date: 10/11/2012
Acceptance date: 24/11/2012
Publication date: 26/12/2012

Abstract

Authors’ conclusions: there is no evidence of developmental delay in children, between 1 and 5 years of age, with severe neonatal hyperbylirubinemia with no symptoms or minor symptoms of acute bilirubin neonatal encephalopathy.

Reviewers’ commentary: it seems that severe neonatal hyperbilirubinemia in newborns of gestational age above 35 weeks, does not affect psychomotor development in the first five years of life. This is consistent with the results of previous studies.

How to cite this article

Aparicio Rodrigo M, Aparicio Sánchez JL. La hiperbilirrubinemia neonatal grave sin encefalopatía significativa precoz no afecta al desarrollo psicomotor. Evid Peditr. 2013;9:5.

AVC | Critically appraised articles

Vandborg PK, Hansen BM, Greisen G, Jepsen M, Ebbesen F. Follow-up of neonates with total serum bilirubin levels ≥ 25 mg/dL: a Danish population-based study. Pediatrics. 2012;130:61-6.
Reviewers: Aparicio Rodrigo M1, Aparicio Sánchez JL2.
1Centro de Salud Entreví­as. Área 1. Madrid. España.
2Servicio de Pediatría. Hospital Dr. José Molina Orosa. Lanzarote. Las Palmas. España.
Correspondence: María Aparicio Rodrigo. Email: maparicio@salud.madrid.org
Reception date: 10/11/2012
Acceptance date: 24/11/2012
Publication date: 26/12/2012

How to cite this article

Aparicio Rodrigo M, Aparicio Sánchez JL. La hiperbilirrubinemia neonatal grave sin encefalopatía significativa precoz no afecta al desarrollo psicomotor. Evid Peditr. 2013;9:5.

References

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  5. Ip S, Chung M, Kulig J, O'Brien R, Sege R, Glicken S; American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. An Evidence-Based Review of Important Issues Concerning Neonatal Hyperbilirubinemia. Pediatrics. 2004;114:e130-53.
  6. Newman TB, Liljestrand P, Jeremy RJ, Ferriero DM, Wu YW, Hudes ES, et al; Jaundice and Infant Feeding Study Team. Outcomes among newborns with total serum bilirubin levels of 25 mg per deciliter or more. N Engl J Med. 2006;354:1889-900.
26/12/2012


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