September 2014. Volume 10. Number 3

Lactobacillus reuterii could reduce pulmonary exacerbations in patients with cystic fibrosis

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Di Nardo G, Oliva S, Menichella A, Pistelli R, De Biase RV, Patriarchi F, et al. Lactobacillus reuteri ATCC55730 in cystic fibrosis. J Pediatr Gastroenterol Nutr. 2014;58:81-6.
Reviewers: Molina Arias M1, Ortega Páez E2.
1Servicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
2CS Maracena. Distrito metropolitano. Granada. España.
Correspondence: Manuel Molina Arias. Email: mma1961@gmail.com
Acceptance date: 28/04/2014
Publication date: 18/06/2014

Abstract

Authors' conclusions: Lactobacillus reuterii reduces pulmonary exacerbations and episodes of otitis in patients with cystic fibrosis with mild-to-moderate lung disease.

Reviewers' commentary: although Lactobacillus reuterii seems to reduce respiratory exacerbations in patients with cystic fibrosis, it remains to be determined how long the effect last, wich the most adequate strain is, and what its effectiveness on lung function over time is.

How to cite this article

Ortega Páez E, Molina Arias M. Lactobacillus reuterii podría reducir las agudizaciones pulmonares en la fibrosis quística. Evid Pediatr. 2014;10:42.

AVC | Critically appraised articles

Di Nardo G, Oliva S, Menichella A, Pistelli R, De Biase RV, Patriarchi F, et al. Lactobacillus reuteri ATCC55730 in cystic fibrosis. J Pediatr Gastroenterol Nutr. 2014;58:81-6.
Reviewers: Molina Arias M1, Ortega Páez E2.
1Servicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
2CS Maracena. Distrito metropolitano. Granada. España.
Correspondence: Manuel Molina Arias. Email: mma1961@gmail.com
Acceptance date: 28/04/2014
Publication date: 18/06/2014

How to cite this article

Ortega Páez E, Molina Arias M. Lactobacillus reuterii podría reducir las agudizaciones pulmonares en la fibrosis quística. Evid Pediatr. 2014;10:42.

References

  1. Infante Pina D, Redecillas Ferreiro S, Torrent Vernetta A, Segarra Cantón O, Maldonado Smith M, Gartner Tizziano L, et al. Optimización de la función intestinal en pacientes con fibrosis quística mediante la administración de probióticos. An Pediatr (Barc). 2008;69:501-5.
  2. Bruzzese E, Raia V, Gaudiello G, Polito G, Buccigrossi V, Formicola V, et al. Intestinal inflammation is a frequent feature of cystic fibrosis and is reduced by probiotic administration. Aliment Pharmacol Ther. 2004;20:813-9.
  3. Bruzzese E, Raia V, Spagnuolo MI, Volpicelli M, De Marco G, Maiuri L, et al. Effect of Lactobacillus GG supplementation on pulmonary exacerbations in patients with cystic fibrosis: a pilot study. Clin Nutr. 2007;26:322-8.
  4. Weiss B, Bujanover Y, Yahav Y, Vilozni D, Fireman E, Efrati O. Probiotic supplementation affects pulmonary exacerbations in patients with cystic fibrosis: a pilot study. Pediatr Pulmonol. 2010;45:536-40.
18/06/2014

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