September 2014. Volume 10. Number 3

The maintenance of a low oxygen saturation in preterm increases the risk of death and necrotizing enterocolitis

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Saugstad OD, Aune D. Optimal oxygenation of extremely low birth weight infants: a meta-analysis and systematic review of the oxygen saturation target studies. Neonatology. 2014;105:55-63.
Reviewers: Carvajal Encina F1, Ibáñez Pradas V2.
1UCIN Hospital de La Serena y Escuela de Medicina Universidad Católica del Norte. La Serena. Elqui. Chile.
2 Servicio de Cirugía Pediátrica. Hospital General de Castellón. Valencia. Valencia. España.
Correspondence: Fernando Carvajal Encina. Email: fcarvajal@ucn.cl
Reception date: 21/08/2014
Acceptance date: 27/08/2014
Publication date: 03/09/2014

Abstract

Authors' conclusions: in extremely low birth weight infants, risk for mortality and necrotizing enterocolitis is increased, and retinopathy of prematurity decreased with a low oxygen saturation target.

Reviewers' commentary: this study offers first class evidence about risk and benefits associated with different ranges of oxygen saturation in low birth weight infants. Although methodological flaws are negligible, concern is raised as oxygen saturation targets used for patients allocation don't fit with clinical practice.

How to cite this article

Carvajal Encina F, Ibáñez Pradas V. El mantenimiento de una saturación de oxígeno baja en prematuros extremos aumentaría el riesgo de muerte y de enterocolitis necrotizante. Evid Pediatr. 2014;10:50.

AVC | Critically appraised articles

Saugstad OD, Aune D. Optimal oxygenation of extremely low birth weight infants: a meta-analysis and systematic review of the oxygen saturation target studies. Neonatology. 2014;105:55-63.
Reviewers: Carvajal Encina F1, Ibáñez Pradas V2.
1UCIN Hospital de La Serena y Escuela de Medicina Universidad Católica del Norte. La Serena. Elqui. Chile.
2 Servicio de Cirugía Pediátrica. Hospital General de Castellón. Valencia. Valencia. España.
Correspondence: Fernando Carvajal Encina. Email: fcarvajal@ucn.cl
Reception date: 21/08/2014
Acceptance date: 27/08/2014
Publication date: 03/09/2014

How to cite this article

Carvajal Encina F, Ibáñez Pradas V. El mantenimiento de una saturación de oxígeno baja en prematuros extremos aumentaría el riesgo de muerte y de enterocolitis necrotizante. Evid Pediatr. 2014;10:50.

References

  1. Askie LM, Brocklehurst P, Darlow BA, Finer N, Schmidt B, Tarnow-Mordi W, et al. NeOProM: neonatal oxygenation prospective meta-analysis collaboration study protocol. BMC Pediatrics. 2011;11:6.
  2. Walsh M, Yao Q, Gettner P, Hale E, Collins M, Hensman A, et al. Impact of a physiologic definition on bronchopulmonary dysplasia rates. Pediatrics. 2004;114:1305-11.
  3. Saugstad OD, Aune D. Optimal oxygenation of extremely low birth weight infants: a meta-analysis and systematic review of the oxygen saturation target studies. Neonatology. 2014;105:55-63. (online suppl. material.)
  4. Saugstad OD, Aune D. In search of the optimal oxygen saturation for extremely low birth weight infants: a systematic review and meta-analysis. Neonatology. 2011;100:1-8.
  5. Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, et al. European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants--2013 update. Neonatology. 2013;103:353-68.

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Sánchez Zaplana H. El dilema del oxígeno en prematuros: la historia continúa. Evid Pediatr. 2014;10:51.
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Linked Comment

CA |

Sánchez Zaplana H. El dilema del oxígeno en prematuros: la historia continúa. Evid Pediatr. 2014;10:51.