June 2023. Volume 19. Number 2

Strategy of early antibiotic therapy in children with sepsis remains a priority

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Khanthathasiri S, Kriengsoontornkij W, Monsomboon A, Phongsamart W, Lapphra K, Wittawatmongkol O, et al. Outcomes of Single-Dose Empirical Antibiotic Treatment in Children With Suspected Sepsis Implemented in the Emergency Department. Pediatr Emerg Care. 2022;38:426-30.

Reviewers: Balado Insunza MN1, Aparicio Rodrigo M2.
1Servicio de Pediatría. Hospital Álvaro Cunqueiro. Vigo. Pontevedra. España.
2Pediatra. CS Entrevías. Facultad de Medicina. Universidad Complutense de Madrid. Madrid. España.
Correspondence: María de las Nieves Balado Insunza. Email: nbalins@gmail.com
Reception date: 02/03/2023
Acceptance date: 12/03/2023
Publication date: 22/03/2023

Abstract

Authors´ conclusions: single-dose empiric antibiotic in the pediatric emergency department is an effective strategy to reduce the time from hospital arrival to antibiotic initiation and may help improve sepsis outcomes in children, reducing length of stay, duration of treatment, pediatric ICU admissions, and mortality.

Reviewers´ commentary: In patients with suspected sepsis, without clinical shock, antimicrobial therapy should be initiated as soon as possible, allowing up to 3 hours for diagnostic investigation and avoiding antibiotic treatment in non-bacterial infections or in non-infectious processes.

How to cite this article

Balado Insunza MN. Aparicio Rodrigo M. La estrategia de antibioterapia precoz en niños con sepsis sigue siendo una prioridad. Evid Pediatr. 2023;19:13.

AVC | Critically appraised articles

Khanthathasiri S, Kriengsoontornkij W, Monsomboon A, Phongsamart W, Lapphra K, Wittawatmongkol O, et al. Outcomes of Single-Dose Empirical Antibiotic Treatment in Children With Suspected Sepsis Implemented in the Emergency Department. Pediatr Emerg Care. 2022;38:426-30.

Reviewers: Balado Insunza MN1, Aparicio Rodrigo M2.
1Servicio de Pediatría. Hospital Álvaro Cunqueiro. Vigo. Pontevedra. España.
2Pediatra. CS Entrevías. Facultad de Medicina. Universidad Complutense de Madrid. Madrid. España.
Correspondence: María de las Nieves Balado Insunza. Email: nbalins@gmail.com
Reception date: 02/03/2023
Acceptance date: 12/03/2023
Publication date: 22/03/2023

How to cite this article

Balado Insunza MN. Aparicio Rodrigo M. La estrategia de antibioterapia precoz en niños con sepsis sigue siendo una prioridad. Evid Pediatr. 2023;19:13.

22/03/2023

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