December 2016. Volume 12. Number 4

Preventing exacerbations in preschool children with asthma. Which of the treatments available is more effective?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Kaiser SV, Huynh T,Bacharier LB, Rosenthal JL,Bakel LA, Parkin PC, et al. Preventing exacerbations in preschoolers with recurrent wheeze: a meta-analysis. Pediatrics. 2016;137(6):pii:e20154496.
Reviewers: Martínez Rubio M.V1, Juanes de Toledo B2.
1CS Los Fresnos. Torrejón de Ardoz. Madrid. España.
2EAP Collado Villalba. Collado Villalba. Madrid. España.
Correspondence: María Victoria Martínez Rubio. Email: victmrubio@gmail.com
Reception date: 02/11/2016
Acceptance date: 04/11/2016
Publication date: 09/11/2016

Abstract

Authors´ conclusions: there is strong evidence to support daily ICS (inhaled corticosteroids) for preventing exacerbations in preschool children with recurrent wheeze, specifically in children with persistent asthma. For preschool children with intermittent asthma or viral triggered wheezing, there is strong evidence to support intermittent ICS for preventing exacerbations.

Reviewers´ commentary: clearly the use of daily ICS is effective in the prevention of exacerbations in children with persistent asthma. For intermittent or viral URTIs (Upper respiratory tract infections) induced exacerbations of asthma, high-dose intermittent ICS appear to play an important role in preventing severe exacerbations.

How to cite this article

Martínez Rubio MV, Juanes de Toledo B. Prevención de reagudizaciones de asma en preescolares. ¿Qué tratamiento es más eficaz? Evid Pediatr. 2016;12:62.

AVC | Critically appraised articles

Kaiser SV, Huynh T,Bacharier LB, Rosenthal JL,Bakel LA, Parkin PC, et al. Preventing exacerbations in preschoolers with recurrent wheeze: a meta-analysis. Pediatrics. 2016;137(6):pii:e20154496.
Reviewers: Martínez Rubio M.V1, Juanes de Toledo B2.
1CS Los Fresnos. Torrejón de Ardoz. Madrid. España.
2EAP Collado Villalba. Collado Villalba. Madrid. España.
Correspondence: María Victoria Martínez Rubio. Email: victmrubio@gmail.com
Reception date: 02/11/2016
Acceptance date: 04/11/2016
Publication date: 09/11/2016

How to cite this article

Martínez Rubio MV, Juanes de Toledo B. Prevención de reagudizaciones de asma en preescolares. ¿Qué tratamiento es más eficaz? Evid Pediatr. 2016;12:62.

References

  1. Pruteanu AI, Chauhan BF, Zhang L, Prietsch SO, Ducharme FL. Inhaled corticosteroids in children with persistent asthma: dose-response effects on growth. Cochrane Database Syst Rev. 2014;7:CD009878.
  2. Chauhan BF, Chartrand C, Ducharme FM. Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults. Cochrane Database Syst Rev. 2013;2:CD009611.
  3. Chong J, Haran C, Chauhan BF, Asher I. Intermittent inhaled corticosteroid therapy versus placebo for persistent asthma in children and adults. Cochrane Database Syst Rev. 2015;7:CD011032.
  4. Castro-Rodriguez JA, Custovic A, Ducharme FM. Treatment of asthma in young children: evidence-based recommendations. Asthma Res Pract. 2016;2:5.
09/11/2016

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