December 2021. Volume 17. Number 4

The BCG vaccine provides additional benefits in high neonatal morbimortality backgrounds.

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Prentice S, Nassanga B, Webb EL, Akello F, Kiwudhu F, Akurut H, et al. BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial. Lancet Infect Dis. 2021;21:993-1003.

Reviewers: Ortega Páez E1, Esparza Olcina MJ2.
1Pediatra. UGC de Maracena. Distrito Granada-Metropolitano. Granada. España.
2Pediatra de Atención Primaria. Madrid. España.
Correspondence: Eduardo Ortega Páez. Email: edortegap@gmail.com
Reception date: 28/11/2021
Acceptance date: 14/12/2021
Publication date: 22/12/2021

Abstract

Authors’ conclusions: the BCG vaccine administered in the first 24 hours of life reduces the incidence of all cause infections, especially in males less than 2500 grams. Its prioritization in high neonatal morbimortality settings might have significant public-health benefits.

Reviewers’ commentary: BCG vaccine at birth compared to its application in the sixth week of life reduces the rate of infections not related to tuberculosis. This is especially relevant in countries with low health resources.

How to cite this article

Ortega Páez E, Esparza Olcina MJ. La BCG proporciona beneficios adicionales en entornos de alta morbimortalidad neonatal. Evid Pediatr. 2021;17:45.

AVC | Critically appraised articles

Prentice S, Nassanga B, Webb EL, Akello F, Kiwudhu F, Akurut H, et al. BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial. Lancet Infect Dis. 2021;21:993-1003.

Reviewers: Ortega Páez E1, Esparza Olcina MJ2.
1Pediatra. UGC de Maracena. Distrito Granada-Metropolitano. Granada. España.
2Pediatra de Atención Primaria. Madrid. España.
Correspondence: Eduardo Ortega Páez. Email: edortegap@gmail.com
Reception date: 28/11/2021
Acceptance date: 14/12/2021
Publication date: 22/12/2021

How to cite this article

Ortega Páez E, Esparza Olcina MJ. La BCG proporciona beneficios adicionales en entornos de alta morbimortalidad neonatal. Evid Pediatr. 2021;17:45.

22/12/2021

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