December 2009. Volume 5. Number 4

Does the order of vaccine injection influence infant pain response?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Artículo valorado críticamente: Ipp M, Parkin PC, Lear N, Goldbach M, Taddio A. Order of vaccine injection and infant pain response. Arch. Pediatr. Adolesc. Med 2009;163(5):469-72
Reviewers: Aparicio Rodrigo M1, Juanes de Toledo B2.
1Centro de Salud Entreví­as. Área 1. Madrid. España.
2 Equipo de Atención Primaria El Espinillo. Área 11. Madrid. España.
Correspondence: María Aparicio Rodrigo. Email: maparicio@salud.madrid.org
Reception date: 30/08/2009
Acceptance date: 01/10/2009
Publication date: 10/12/2009

Abstract

Authors' conclusions: pain was reduced when the DPTaPHib vaccine was administered before the PCV in infants undergoing routine vaccination. On the basis of these results, we recommend that the order of vaccines be the DPTaP-Hib vaccine followed by the PCV.

Reviewers' commentary: infant pain response during routine intramuscular inmunization was affected by the order of administration of the vaccines. When two vaccines are given together, the least painful should be administered first. This strategy is simple, effective, cost free, and easily incorporated into clinical practice.

How to cite this article

Aparicio Rodrigo M, Juanes de Toledo B. ¿Influye el orden de las vacunas en el dolor del lactante? Evid Pediatr. 2009;5:77.

AVC | Critically appraised articles

Artículo valorado críticamente: Ipp M, Parkin PC, Lear N, Goldbach M, Taddio A. Order of vaccine injection and infant pain response. Arch. Pediatr. Adolesc. Med 2009;163(5):469-72
Reviewers: Aparicio Rodrigo M1, Juanes de Toledo B2.
1Centro de Salud Entreví­as. Área 1. Madrid. España.
2 Equipo de Atención Primaria El Espinillo. Área 11. Madrid. España.
Correspondence: María Aparicio Rodrigo. Email: maparicio@salud.madrid.org
Reception date: 30/08/2009
Acceptance date: 01/10/2009
Publication date: 10/12/2009

How to cite this article

Aparicio Rodrigo M, Juanes de Toledo B. ¿Influye el orden de las vacunas en el dolor del lactante? Evid Pediatr. 2009;5:77.

References

  1. Hatfield LA, Gusic ME, Dyer A, Polomano R. Analgesic properties of oral sucrose during routine immunizations at 2 and 4 months of age. Pediatrics. 2008;121:e327-34.
  2. Dilli D, Kücük IG, Dallar Y. Interventions to reduce pain duringvaccination in infancy. J. Pediatr. 2009;254:385-90.
  3. Ipp M, Cohen E, Goldbach M, Macarthur C. Effect of choice of measles-mumpsrubella vaccine on immediate vaccination pain in infants. Arch Pediatr Adolesc Med. 2004;158:323-6.
  4. Boivin J-M, Poupon-Lemarquis L, Iraqi W, Fay R, Schmitt C and Rossignol P. A multifactorial strategy of pain management is associated with less pain in scheduled vaccination of children. A study realized by family practitioners in 239 children aged 4–12 years old. Family Practice. 2008;7:1-7.
10/12/2009

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