June 2015. Volume 11. Number 2

La calprotectina fecal puede resultar útil en la sospecha de enfermedad inflamatoria intestinal

 
 
 
 
 
 
 
 
 
 
Rating: 0 (0 Votes)
Newsletter Free Subscription
Regularly recieve most recent articles by e-mail
Subscribe
Print
Add to library
Discuss this article

AVC | Critically appraised articles

Degraeuwe PL, Beld MP, Ashorn M, Canani RB, Day AS, Diamanti A, et al. Faecal calprotectin in suspected paediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2015;60:339-46.
Reviewers: Ortega Páez E1, Pérez-Moneo Agapito B2.
1CS Maracena. Distrito Granada-Metropolitano. Granada. España.
2Hospital Universitario Infanta Leonor. Madrid. España.
Correspondence: Eduardo Ortega Páez. Email: edortegap@gmail.com
Reception date: 15/05/2015
Acceptance date: 29/05/2015
Publication date: 03/06/2015

Abstract

Authors´ conclusions: fecal calprotectin has high accuracy for diagnosis of inflammatory bowel disease (IBD) in tertiary referral centers. Both the concentration of calprotectin and the child's age are associated with the diagnosis of IBD.

Reviewers´ commentary: fecal calprotectin is a determination of high diagnostic performance in childhood inflammatory bowel disease. Its usefulness would be different according to the clinical stage. In clinical settings with a high prevalence of IBD, specific to specialized care, it would be most useful for the selection of those patients more appropriate to undergo endoscopy and confirm the diagnosis. However, in low prevalence settings, as in primary health care centers, it would be of greater service to detect the presence of the disease.

How to cite this article

Ortega Páez E, Pérez-Moneo Agapito B. La calprotectina fecal puede resultar útil en la sospecha de enfermedad inflamatoria intestinal. Evid Pediatr. 2015;11:30.

AVC | Critically appraised articles

Degraeuwe PL, Beld MP, Ashorn M, Canani RB, Day AS, Diamanti A, et al. Faecal calprotectin in suspected paediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2015;60:339-46.
Reviewers: Ortega Páez E1, Pérez-Moneo Agapito B2.
1CS Maracena. Distrito Granada-Metropolitano. Granada. España.
2Hospital Universitario Infanta Leonor. Madrid. España.
Correspondence: Eduardo Ortega Páez. Email: edortegap@gmail.com
Reception date: 15/05/2015
Acceptance date: 29/05/2015
Publication date: 03/06/2015

How to cite this article

Ortega Páez E, Pérez-Moneo Agapito B. La calprotectina fecal puede resultar útil en la sospecha de enfermedad inflamatoria intestinal. Evid Pediatr. 2015;11:30.

References

  1. Timmer A, Behrens R, Buderus S, Findeisen A, Hauer A, Keller KM, et al. Childhood onset inflammatory bowel disease: predictors of delayed diagnosis from the CEDATA German-language pediatric inflammatory bowel disease registry. J Pediatr. 2011;158:467-73.
  2. Henderson P, Anderson NH, Wilson DC. The diagnostic accuracy of fecal calprotectin during the investigation of suspected pediatric inflammatory bowel disease: a systematic review and meta-analysis. Am J Gastroenterol. 2014;109:637-45.
  3. Lyman GH, Kuderer NM. The strengths and limitations of meta-analyses based on aggregate data. BMC Med Res Methodol. 2005;5:14.
  4. Medina Benítez E, Fuentes Lugo D, Suárez Cortina L, Prieto Bozano G. Emfermedad inflamatoria intestinal. En: Asociación Española de Pediatría [en línea] [consultado el 29/05/2015]. Disponible en: http://www.aeped.es/sites/default/files/documentos/eii.pdf
  5. Kostakis ID, Cholidou KG, Vaiopoulos AG, Vlachos IS, Perrea D, Vaos G. Fecal calprotectin in pediatric inflammatory bowel disease: a systematic review. Dig Dis Sci. 2013;58:309-19.
  6. Waugh N, Cummins E, Royle P, Kandala NB, Shyangdan D, Arasaradnam R, et al. Faecal calprotectin testing for differentiating amongst inflammatory and non-inflammatory bowel diseases: systematic review and economic evaluation. Health Technol Assess. 2013;17:1-211.
03/06/2015

Linked Comment