September 2010. Volume 6. Number 3

A metanalysis does not seem to confirm the hypothetical relation between water purification by-products and slow fetal growth or prematurity

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Grellier J, Bennett J, Patelarou E, Smith RB, Toledano MB, Rushton L,et al. Exposure to disinfection by-products, fetal growth, and prematurity: a systematic review and meta-aalysis. Epidemiology. 2010;21:300–13
Reviewers: Esparza Olcina MJ1, García Vera C2.
1Centro de Salud Barcelona. Móstoles. Madrid. España.
2CS Sagasta-Ruiseñores. Zaragoza. España.
Correspondence: María Jesús Esparza Olcina. Email: mjesparza8@gmail.com
Reception date: 27/07/2010
Acceptance date: 26/07/2010
Publication date: 30/07/2010

Abstract

Authors’ conclusions: there is no evidence of association between water-purification by-products in water consumed by the mother and effects on fetal growth or prematurity. There has only been found a certain degree of relation with newborns small for gestational age.

Reviewers’ commentary: this systematic review and metanalysis of epidemiological studies may have included some biases due to the impossibility of a direct measure of the risk factor, and the possible mobility of the population. The conclusions have to be considered with precaution although the effects seem to be very small

How to cite this article

Esparza Olcina MJ, García Vera C. Un metanálisis no parece confirmar la hipotética relación entre productos derivados de la desinfección del agua potable y el retraso del crecimiento fetal o la prematuridad. Evid Pediatr. 2010;6:52.

AVC | Critically appraised articles

Grellier J, Bennett J, Patelarou E, Smith RB, Toledano MB, Rushton L,et al. Exposure to disinfection by-products, fetal growth, and prematurity: a systematic review and meta-aalysis. Epidemiology. 2010;21:300–13
Reviewers: Esparza Olcina MJ1, García Vera C2.
1Centro de Salud Barcelona. Móstoles. Madrid. España.
2CS Sagasta-Ruiseñores. Zaragoza. España.
Correspondence: María Jesús Esparza Olcina. Email: mjesparza8@gmail.com
Reception date: 27/07/2010
Acceptance date: 26/07/2010
Publication date: 30/07/2010

How to cite this article

Esparza Olcina MJ, García Vera C. Un metanálisis no parece confirmar la hipotética relación entre productos derivados de la desinfección del agua potable y el retraso del crecimiento fetal o la prematuridad. Evid Pediatr. 2010;6:52.

References

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  2. World Health Organization (WHO). Thrihalomethanes in drinking water: background document for developments of WHO guidelines for drinking-water quality. WHO:Geneva; 2005.
  3. Proyecto Infancia y Medio Ambiente [página web en Internet] [consultado: 25-7-2010]. Disponible en: http://www.infanciaymedioambiente.org/
  4. Santa Marina L, Ayerdi M, Lertxundi A, Basterretxea M, Alvare JI, Arranz L, et al. Concentraciones de trihalometanos y ácidos haloacéticos en el agua de consumo  y estimación de su ingesta durante el embarazo en la cohorte INMA-Guipúzcoa (España). Gac Sanit. 2010, 4 de mayo (en prensa).
  5. Freire C, Soler R, Fernández MF, Villanueva CM, Grimalt JO, Olea N. Valores de trihalometanos en agua de consumo de la provincia de Granada, España. Gac Sanit. 2008;22:520-6.
  6. Sistema de Información Nacional de Aguas de Consumo [consultado: 25-7-2010]. Disponible en: http://sinac.msc.es/sinac/ 
30/07/2010

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