September 2018. Volume 14. Number 2

Inhaled corticosteroid treatment for bronchopulmonary dysplasia: lights and shadows

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Bassler D, Shinwell ES, Hallman M, Jarreau PH, Plavka R, Carnielli V, Meisner C, Engel C, Koch A, Kreutzer K, van den Anker JN, Schwab M, Halliday HL, Poets CF; Neonatal European Study of Inhaled Steroids Trial Group. Long-Term Effects of Inhaled Budesonide for Bronchopulmonary Dysplasia. N Engl J Med. 2018 Jan 11;378(2):148-157.
Reviewers: Aizpurua Galdeano P1, Cuestas Montañés E2.
1CS Amara Berri. San Sebastián. España.
2Servicio de Pediatría y Neonatología. Hospital Privado. Centro Formador. Facultad de Ciencias Médicas. Universidad Nacional de Córdoba. Córdoba. Argentina.
Correspondence: Pilar Aizpurua Galdeano. Email: 19353pag@gmail.com
Reception date: 03/09/2018
Acceptance date: 12/09/2018
Publication date: 19/09/2018

Abstract

Authors’ conclusions: among surviving extremely preterm infants, the rate of neurodevelopmental disability at 2 years did not differ significantly between infants who received early inhaled budesonide for the prevention of bronchopulmonary dysplasia and those who received placebo, but the mortality rate was higher among those who received budesonide.

Reviewers’ commentary: doubts persist about the benefit-risk relationship of early inhaled corticosteroid treatment in extremely premature infants who require assisted ventilation.

How to cite this article

Aizpurua Galdeano P, Cuestas Montañés E. Corticoides inhalados para la displasia broncopulmonar: luces y sombras. Evid Pediatr. 2018;14:20.

AVC | Critically appraised articles

Bassler D, Shinwell ES, Hallman M, Jarreau PH, Plavka R, Carnielli V, Meisner C, Engel C, Koch A, Kreutzer K, van den Anker JN, Schwab M, Halliday HL, Poets CF; Neonatal European Study of Inhaled Steroids Trial Group. Long-Term Effects of Inhaled Budesonide for Bronchopulmonary Dysplasia. N Engl J Med. 2018 Jan 11;378(2):148-157.
Reviewers: Aizpurua Galdeano P1, Cuestas Montañés E2.
1CS Amara Berri. San Sebastián. España.
2Servicio de Pediatría y Neonatología. Hospital Privado. Centro Formador. Facultad de Ciencias Médicas. Universidad Nacional de Córdoba. Córdoba. Argentina.
Correspondence: Pilar Aizpurua Galdeano. Email: 19353pag@gmail.com
Reception date: 03/09/2018
Acceptance date: 12/09/2018
Publication date: 19/09/2018

How to cite this article

Aizpurua Galdeano P, Cuestas Montañés E. Corticoides inhalados para la displasia broncopulmonar: luces y sombras. Evid Pediatr. 2018;14:20.

19/09/2018

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