March 2011. Volume 7. Number 1

Ondansetron oral administration could be cost-effective in the treatment of vomiting in children with dehydration secondary to gastroenteritis

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Freedman SB, Steiner MJ, Chan KJ. Oral Ondansetron Administration in Emergency Departments to Children with Gastroenteritis: An Economic Analysis. PLoS Med. 2010;7:e1000350.
Reviewers: Esparza Olcina MJ1, Perdikidis Olivieri L2.
1Centro de Salud Barcelona. Móstoles. Madrid. España.
2EAP Juncal. Torrejón de Ardoz. Madrid. España.
Correspondence: María Jesús Esparza Olcina. Email: mjesparza8@gmail.com
Reception date: 19/01/2011
Acceptance date: 24/01/2011
Publication date: 27/01/2011

Abstract

Authors' conclusions: in countries where intravenous rehydration is often used, emergency department administration of oral ondansetron to children with dehydration and vomiting secondary to gastroenteritis results in significant monetary savings compared to non-ondansetron policy.

Reviewers' commentary: according to this well conducted economic analysis, ondansetron administration in the emergency department to children with vomiting and mild-moderate dehydration secondary to gastroenteritis, produces important savings, much higher in the United Statesthan in Canada, there remain some doubts about the drug’s effectivity because the data used in this study are based in a meta-analysis with important methodological limitations.

How to cite this article

Esparza Olcina MJ, Perdikidis Olivieri L. La administración de ondansetrón por vía oral podría ser coste efectiva para tratar los vómitos en niños con deshidratación secundaria a gastroenteritis. Evid Pediatr. 2011;7:11.

AVC | Critically appraised articles

Freedman SB, Steiner MJ, Chan KJ. Oral Ondansetron Administration in Emergency Departments to Children with Gastroenteritis: An Economic Analysis. PLoS Med. 2010;7:e1000350.
Reviewers: Esparza Olcina MJ1, Perdikidis Olivieri L2.
1Centro de Salud Barcelona. Móstoles. Madrid. España.
2EAP Juncal. Torrejón de Ardoz. Madrid. España.
Correspondence: María Jesús Esparza Olcina. Email: mjesparza8@gmail.com
Reception date: 19/01/2011
Acceptance date: 24/01/2011
Publication date: 27/01/2011

How to cite this article

Esparza Olcina MJ, Perdikidis Olivieri L. La administración de ondansetrón por vía oral podría ser coste efectiva para tratar los vómitos en niños con deshidratación secundaria a gastroenteritis. Evid Pediatr. 2011;7:11.

References

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  2. Ochoa Sangrador C, Orejón de Luna G. Una dosis de ondansetrón parece reducir los vómitos en pacientes con gastroenteritis aguda atendidos en servicios de urgencias. Evid Pediatr. 2008;4:73.
  3. Parada Ricart E, Inoriza Belurze JM, Plaja Roman P. Gastroenteritis aguda: coste de una causa de ingreso potencialmente evitable. An Pediatr (Barc). 2007;67:368-73.
  4. Utilización de la rehidratación oral en urgencias. Encuesta nacional Sociedad Española de Urgencias de Pediatría. An Pediatr (Barc). 2004;60:243-8.
  5. Azpurua L, Balaguer A. Una dosis de ondansetrón oral disminuye los vómitos en niños con gastroenteritis pero no modifica la necesidad de ingreso hospitalario. Evid Pediatr. 2006;2:52.
  6. González Rodriguez MP. Metaanálisis: utilización de ondansetrón en los vómitos en la gastroenteritis aguda en los niños. Evid Pediatr. 2009;5:76.
27/01/2011

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